Dev102210 1023..1027
نویسنده
چکیده
Skeletal stem cells (SSCs) reside in the postnatal bonemarrowand give rise to cartilage, bone, hematopoiesis-supportive stroma and marrow adipocytes indefined in vivoassays.These lineagesemerge inaspecific sequence during embryonic development and post natal growth, and together comprise a continuous anatomical system, the bone-bone marroworgan.SSCsconjoin skeletal andhematopoieticphysiology, and are a tool for understanding and ameliorating skeletal and hematopoietic disorders. Here and in the accompanying poster, we concisely discuss the biology of SSCs in the context of the development and postnatal physiology of skeletal lineages, to which their use in medicine must
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